- Sentinel 1.1
- Sentinel 3: Homeworld 1.0.0
- Sentinel Pro 1.0.4
- SEO Extract 5.0.4
- SEO PowerSuite 35.0
- SEO SpyGlass 5.14.6
- SEOAuditor 1.2
- SEOggestor 1.2
- SEOPingler 1.2
- SEOSpyder 1.0
- Separator 0.6.1
- Sepialise Me 1.1
- SepINRIA 1.8
- SepPreview_CS2 2.1
- SepPreview_CS3 3.0.3
- Septavo Tangram 1.2.1
- Sequel Pro 1.0.2
- Sequence 2.0.3
- Sequence Analysis 2.0.0
- Sequencer 1.3
- SequenceSketcher 1.0.7
- Sequencher 5.1
- Sequential 2.1.2
- Sequenz 1.2
- Sequenzetto 1.0.5
- Sequimago 0.1
- Sequoia 2.1
- SERank 2.6.3
- Serato DJ 1.7
- Serato DJ Intro 1.2.2
- Serchilo 1.0
- Serenade 1.0.2
- SerGen 3.5
- Serial 1.1.3
- Serial Cloner 2.6.1
- Serial Mail 4.6
- SerialBase 1.0.1
- Serializer 1.2
- SerialLetter 1.2
- SerialMailer 7.7.9
- SerialParallels 1.0
- SerialPort X 2.2
- SerieFoot 1.0.8
- Serious Sam 3: BFE 1.0
- Serisag 4.490
- SERMON X 1.0.2
- Serna Free XML Editor 4.2
- Serna XML Editor 4.1.5
- Serpent of Isis: Your Journey Continues 1.0
- servebox 1.0
- Server Control 0.1
- Server Manager 1.0.5
- Server Monitor 1.0.0.3
- Server Scout 0.9.8b
- Server Siren 1.1
- Server Status Monitor 1.0
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