- Santa's Gizmo 2.1
- Santa's Super Friends 2.0
- Santaduck Toolpak for UT2004 3.3
- SantaSnaps 1.0.1
- Sanyo H.264 Fixer 1.1
- SAOImage DS9 7.2
- Sapiens 1.3
- Sapling 1.1
- SAPO Messenger 1.0
- Sapphire Plug-ins 7.02
- Sapphire Plug-ins for Apple FxPlug Products 2.05
- Sarah Maribu and the Lost World 1.0
- sArchiver 3.8.15
- Sarien 0.7.0a2
- SAT Vocab Prep 1.4.0
- Satellite Eyes 1.3.3
- Satellite Image Browser 2.0
- Satimage osax 3.6.1
- Satori
- Satstat 1.1
- Saturn 2.0
- Saubermacher 0.1
- Sauerbraten 1.5
- Savage 2 2.1
- Savage: The Battle for Newerth 1.0.1
- Save Album Art to Album Folder 4.3
- Save My Whiteboard X 2.0
- Save the Farley Mowat 1.1.5
- Save Your Screen 2.0
- SaveCircle 1.2
- SaveHollywood 2.0
- SaveMe 1.3.1
- SaverDesktop 1.1
- SaverLab 1.7.4
- SaverPreview 1.1
- Savin Printer Drivers for OS X 10.0
- Saving Private Sheep 1.0.0
- Savings 1.6.1
- Savings Bond Tracker 2.6.0
- Savitar 1.6.1
- Savvy Clipboard 2.9
- SavvyDox 2.0
- Sawmill 8.7.3.2
- say 0.3b
- Say Cheese 2.9
- Say It Save It 2.1
- Say What 1.1.8
- Say-iTunes 1.0
- SB-World 1.0.1
- sBackup 1.7
- SBArt 4.3
- sBlaster 1.02.1
- SBook5 5.1
- SBWrapper 1.3.5.3.1
- Sc21 1.0.1
- Scalare 1.0b61
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